The possible association between isotretinoin (Accutane) use remains controversial.
Part of the reason for the uncertainty is the relatively high incidence of mood disorders among acne sufferers, particularly those with severe cystic acne for whom isotretinoin may be indicated.
The articles below discuss research into the potential affects of isotretinoin on mood and depression.
Br J Dermatol. 2010 Dec;163(6):1323-9.
McGrath EJ, Lovell CR, Gillison F, Darvay A, Hickey JR, Skevington SM.
Kinghorn Dermatology Unit, Royal United Hospital, Bath BA1 3NG, UK.
Abstract
BACKGROUND: Isotretinoin is an efficacious treatment for acne, but has been controversially linked with depression. |
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